Guangchun Bai Selected Research

Tuberculosis (Tuberculoses)

1/2022	Cyclic-di-AMP Phosphodiesterase Elicits Protective Immune Responses Against Mycobacterium tuberculosis H37Ra Infection in Mice.
1/2022	c-di-AMP Accumulation Regulates Growth, Metabolism, and Immunogenicity of Mycobacterium smegmatis.
1/2018	Regulation of the CRISPR-Associated Genes by Rv2837c (CnpB) via an Orn-Like Activity in Tuberculosis Complex Mycobacteria.
1/2016	Characterization of a cAMP responsive transcription factor, Cmr (Rv1675c), in TB complex mycobacteria reveals overlap with the DosR (DevR) dormancy regulon.
7/2014	Deletion of the cyclic di-AMP phosphodiesterase gene (cnpB) in Mycobacterium tuberculosis leads to reduced virulence in a mouse model of infection.
10/2011	Dysregulation of serine biosynthesis contributes to the growth defect of a Mycobacterium tuberculosis crp mutant.
1/2009	cAMP levels within Mycobacterium tuberculosis and Mycobacterium bovis BCG increase upon infection of macrophages.
1/2009	Rv1675c (cmr) regulates intramacrophage and cyclic AMP-induced gene expression in Mycobacterium tuberculosis-complex mycobacteria.
11/2007	The Mycobacterium bovis BCG cyclic AMP receptor-like protein is a functional DNA binding protein in vitro and in vivo, but its activity differs from that of its M. tuberculosis ortholog, Rv3676.
11/2005	Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein.

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Guangchun Bai Research Topics

Disease

13	Infections 01/2024 - 11/2007
10	Tuberculosis (Tuberculoses) 01/2022 - 11/2005
2	Autolysis 12/2021 - 01/2020
1	Human Influenza (Influenza) 01/2024
1	Bacterial Pneumonia 01/2024
1	Persistent Infection 12/2021
1	Endocarditis 12/2021
1	Pneumococcal Infections 01/2020
1	Bites and Stings (Sting) 01/2020
1	Pneumococcal Pneumonia 01/2020
1	Otitis 05/2013
1	Pneumonia (Pneumonitis) 05/2013
1	Bacterial Infections (Bacterial Infection) 05/2013
1	Plague (Bubonic Plague) 08/2010

Drug/Important Bio-Agent (IBA)

8	cyclic diadenosine phosphateIBA 01/2022 - 02/2014
5	Transcription Factors (Transcription Factor)IBA 01/2020 - 11/2005
4	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 01/2022 - 07/2014
3	DNA (Deoxyribonucleic Acid)IBA 12/2021 - 01/2016
3	Proteins (Proteins, Gene)FDA Link 12/2018 - 11/2007
2	VaccinesIBA 01/2022 - 01/2022
2	InterferonsIBA 01/2020 - 01/2018
2	Cyclic AMP (AMP, Cyclic)IBA 12/2018 - 11/2007
1	Pneumococcal Vaccines (Pneumococcal Polysaccharide Vaccine)IBA 01/2024
1	Bacterial VaccinesIBA 01/2024
1	AntigensIBA 01/2022
1	Adenosine Triphosphate (ATP)IBA 12/2021
1	purineIBA 12/2021
1	AcidsIBA 12/2021
1	Adenosine Diphosphate (ADP)IBA 12/2021
1	Anti-Bacterial Agents (Antibiotics)IBA 12/2021
1	EnzymesIBA 12/2021
1	Vancomycin FDA LinkGeneric 12/2021
1	bis(3',5')-cyclic diguanylic acidIBA 01/2018
1	OligonucleotidesIBA 01/2018
1	Adenosine Monophosphate (AMP)IBA 07/2017
1	VitaminsIBA 05/2013
1	PyridoxalIBA 05/2013
1	phosphoserine aminotransferase (phosphoserine transaminase)IBA 10/2011
1	Betahistine (Serc)IBA 10/2011
1	Serine (L-Serine)FDA Link 10/2011
1	RNA (Ribonucleic Acid)IBA 08/2010
1	Indicators and Reagents (Reagents)IBA 01/2009
1	AlbuminsIBA 01/2009
1	Culture MediaIBA 01/2009
1	Adenosine (Adenocard)FDA LinkGeneric 01/2009
1	Cyclic AMP Receptors (Cyclic AMP Receptor)IBA 11/2007